drugset / Trial / NCT06540391

A Phase 1b Trial to Evaluate Safety of MB097 in Combination With Pembrolizumab in Melanoma Patients

NCT06540391

Phase 1 Active not recruiting 41 enrolled Microbiotica Ltd Merck Sharp & Dohme LLC · collab
RandomizedParallel-groupOpen-labelTreatment

Summary

A Phase 1b study to evaluate the safety and tolerability of MB097 given in combination with pembrolizumab in patients with melanoma who demonstrate primary resistance to anti-PD1 therapy.

Timeline

Start
2024-08-28
Primary completion
2025-12
Completion
2027-08

Drugs

EvaluationDrugModalityDoseRoute
Subject MB097 Other / unclassified Oral
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous
Background Vancomycin Other / unclassified 125 mg

Indications