drugset / Trial / NCT06541314

Fluzoparib Neoadjuvant Therapy for Ovarian Cancer

NCT06541314

Phase 2 Unknown 48 enrolled Qilu Hospital of Shandong University
NaSingle-groupOpen-labelTreatment

Summary

This study is an interventional, single-arm, open-label clinical trial. To evaluate the safety and efficacy of Fluzoparib as neoadjuvant therapy in patients with FIGO stage III and IV , BRCA mutations or HRD positive epithelial ovarian cancer who cannot achieve R0 surgery as assessed by imaging (Suidan's CT score) or laparoscopy (Fagotti score), or cannot tolerate surgery.

Timeline

Start
2024-06-18
Primary completion
2026-05-31
Completion
2026-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Fluzoparib Small molecule 150 mg Oral

Indications