drugset / Trial / NCT06545500

A Phase IIb Study of Glycopyrrolate Inhalation Solution Over 1 Week in Subjects With COPD

NCT06545500

Phase 2 Completed 46 enrolled Verona Pharma, Inc.
RandomizedCrossoverTriple-blindTreatment

Summary

This study is a randomized, double-blind, placebo-controlled complete block cross-over study designed to assess the efficacy, safety, and pharmacokinetics of 3 dose levels of glycopyrrolate inhalation solution delivered twice daily via standard jet nebulizer over three 1-week active treatment periods and one 1-week placebo period in subjects with chronic obstructive pulmonary disease (COPD).

Timeline

Start
2024-08-16
Primary completion
2025-01-02
Completion
2025-01-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Glycopyrrolate Small molecule 14 ug Inhaled
Subject Glycopyrrolate Small molecule 42.5 ug Inhaled
Subject Glycopyrrolate Small molecule 85 ug Inhaled