drugset / Trial / NCT06547164
A Study to Investigate the Pharmacokinetics of Midazolam After Repeated Doses of Camizestrant (AZD9833) and to Investigate the Pharmacokinetics of Camizestrant When Administered Alone and in Combination With Carbamazepine in Healthy Post-Menopausal Female Participants
Non-randomizedSequentialOpen-labelTreatment
Summary
This study will be conducted in order to determine the effect of repeated oral doses of camizestrant on the pharmacokinetics (PK) of midazolam and to determine the effect of repeated oral titrated doses of carbamazepine on the PK of camizestrant in healthy post-menopausal female participants.
Timeline
- Start
- 2024-08-27
- Primary completion
- 2025-08-20
- Completion
- 2025-08-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Camizestrant | Other / unclassified | — | Oral |
| Subject | Carbamazepine | Small molecule | — | Oral |
| Subject | Midazolam | Small molecule | — | Oral |
Indications
No indication recorded.