drugset / Trial / NCT06549335

Zanubrutinib, Obinutuzumab and Lenalidomide (ZGR) in High-risk Treatment-naive Patients with Follicular Lymphoma (FL)

NCT06549335 ↗

Phase 2 Not yet recruiting 66 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, multiple-centers, open-label, single-arm clinical study designed to evaluate the efficacy and safety of Zanubrutinib, Obinutuzumab, and Lenalidomide (ZGR) in high-risk treatment-naive patients with follicular lymphomas

Timeline

Start
2024-12-01
Primary completion
2026-12-01
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified 25 mg Oral
Subject Obinutuzumab Monoclonal antibody 1000 mg Intravenous
Subject Zanubrutinib Small molecule 160 mg Oral

Indications