ADC-induced Neurotoxicity Treated With Duloxetine

Summary

RATIONALE: Duloxetine may lessen peripheral neuropathy caused by chemotherapy. It is not yet known whether duloxetine is effective in treating peripheral neuropathy caused by antibody-drug conjugate. PURPOSE: This single arm phase II trial is studying duloxetine to see how well it works in treating peripheral neuropathy caused by antibody-drug conjugate in patients with cancer.

Timeline

Start

2024-08-06

Primary completion

2025-12-30

Completion

2025-12-30

Drugs

Indications