drugset / Trial / NCT06553027
To Evaluate the Efficacy of CVN424 in Parkinson's Disease Participants With Motor Complications
RandomizedParallel-groupQuadruple-blindTreatment
Summary
This is a randomized, double-blind, placebo-controlled, multicenter study in participants with Parkinson's disease (PD) with motor fluctuations. Participants will be randomized to receive once-daily oral doses of either 75 milligrams (mg) CVN424 or 150 mg CVN424, or a matching placebo for 12 weeks. Participants who successfully complete this study and retain eligibility/suitability will be invited to participate in a future open-label extension (OLE) study.
Timeline
- Start
- 2024-09-20
- Primary completion
- 2026-08
- Completion
- 2026-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | SOLENGEPRAS | Small molecule | 75 mg | Oral |
| Subject | SOLENGEPRAS | Small molecule | 150 mg | Oral |