drugset / Trial / NCT06553768

Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)

NCT06553768

Phase 3 Active not recruiting 90 enrolled Mirum Pharmaceuticals, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to determine whether the investigational treatment (maralixibat) is safe and effective in pediatric and adult participants who have cholestatic liver disease with pruritus that has been refractory to other therapies, and who have no other treatment options.

Timeline

Start
2024-10-14
Primary completion
2026-10
Completion
2027-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Maralixibat Small molecule 300 ug/kg Oral

Indications

No indication recorded.