drugset / Trial / NCT06554639
A Drug-Drug Interaction Study of Diltiazem and MK-5684 in Healthy Adult Male Participants (MK-5684-011)
Non-randomizedSequentialOpen-labelTreatment
Summary
Researchers have designed a study medicine called MK-5684 as a new way to treat prostate cancer. The purpose of this study is to learn what happens to MK-5684 in a person's body over time (a pharmacokinetic or PK study). Researchers will compare what happens to MK-5684 in the body when it is given with and without another medicine called diltiazem.
Timeline
- Start
- 2024-07-11
- Primary completion
- 2024-08-05
- Completion
- 2024-08-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Diltiazem | Small molecule | 240 mg | Oral |
| Subject | Opevesostat | Small molecule | — | Oral |
| Background | Fludrocortisone | Other / unclassified | 0.05 mg | Oral |
| Background | Prednisone | Other / unclassified | 2.5 mg | Oral |
| Background | Prednisone | Other / unclassified | 5 mg | Oral |