drugset / Trial / NCT06557278
Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer
NaSingle-groupOpen-labelTreatment
Summary
Experimental immunotherapy in chemotherapy-refractory and immunotherapy-refractory metastatic colorectal cancer patients that have progressed, or are intolerant to, Longsurf (TAS-102) +/- Avastin (bevacizumab) or Stivarga (regorafenib) or Fruzaqla (fruquintinib) combining experimental AlloStim with an anti-programmed death ligand 1 (PD-L1) checkpoint inhibitor drug.
Timeline
- Start
- 2026-11
- Primary completion
- 2028-06
- Completion
- 2028-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | AlloStim | Cell therapy | — | Other |
| Subject | Avelumab | Monoclonal antibody | 800 mg | — |