drugset / Trial / NCT06557278

Combined AlloStim+Anti-PD-L1 in 4L MSS Metastatic Colorectal Cancer

NCT06557278

Phase 2 Withdrawn Mirror Biologics, Inc.
NaSingle-groupOpen-labelTreatment

Summary

Experimental immunotherapy in chemotherapy-refractory and immunotherapy-refractory metastatic colorectal cancer patients that have progressed, or are intolerant to, Longsurf (TAS-102) +/- Avastin (bevacizumab) or Stivarga (regorafenib) or Fruzaqla (fruquintinib) combining experimental AlloStim with an anti-programmed death ligand 1 (PD-L1) checkpoint inhibitor drug.

Timeline

Start
2026-11
Primary completion
2028-06
Completion
2028-11

Drugs

EvaluationDrugModalityDoseRoute
Subject AlloStim Cell therapy Other
Subject Avelumab Monoclonal antibody 800 mg

Indications