drugset / Trial / NCT06557330

MRD Guided De-intensification of Bendamustine/Rituximab for Indolent Non-Hodgkin Lymphoma

NCT06557330

Phase 2 Not yet recruiting 24 enrolled Fox Chase Cancer Center Adaptive Biotechnologies · collab
NaSingle-groupOpen-labelDiagnostic

Summary

This is a phase II pilot, single arm, open label study designed to assess the efficacy, safety, and feasibility of MRD adapted duration of BR for untreated or R/R iNHL.

Timeline

Start
2025-06
Primary completion
2027-09-29
Completion
2028-03-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Bendamustine Small molecule 90 mg/m2 Intravenous
Subject Rituximab Monoclonal antibody 375 mg/m2 Intravenous