Extending the Time Window for Intravenous Tenecteplase in Patients With Distal Medium Vessel Occlusions Stroke

Summary

To assess the safety and efficacy of beyond time window TNK intravenous thrombolysis for distal Medium Vessel Occlusion (MeVO) related stroke in a prospective randomized clinical trial.

Timeline

Start

2024-10-02

Primary completion

2026-09-01

Completion

2026-12-01

Publications

• Jing X, Nogueira RG, Nguyen T, Abdalkader M, Al-Qudah AM, Tao C, Li R, Sun J, Zhu Y, Wang L, Chao Z, Liu T, Song J, Saver JL, Hu W. Extending the time window for intravenous tenecteplase in patients with distal medium vessel occlusions stroke: study protocol and rationale. Stroke Vasc Neurol. 2026 Apr 13:svn-2025-004727. doi: 10.1136/svn-2025-004727. Online ahead of print.

Drugs

Indications