drugset / Trial / NCT06560645

A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

NCT06560645 ↗

Phase 1 Terminated 42 enrolled Prelude Therapeutics
NaSequentialOpen-labelTreatment

Summary

This is a Phase 1 study to determine the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of PRT7732 in patients with select advanced or metastatic solid tumors with a SMARCA4 mutation.

Timeline

Start
2024-11-04
Primary completion
2026-01-28
Completion
2026-01-28

Outcome

Outcome not reported

Stopped (Business): “Sponsor decision”

Drugs

EvaluationDrugModalityDoseRoute
Subject PRT7732 Other / unclassified — Oral