drugset / Trial / NCT06561009

Safety and Efficacy of BAFFR CART for Relapsed/ Refractory Neuromyelitis Optica Spectrum Disorder

NCT06561009 ↗

Phase 1/2 Not yet recruiting 20 enrolled Tianjin Medical University General Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, single-arm, dose-escalation study in up to 20 participants with relapsed/refractory Neuromyelitis Optica Spectrum Disorders (NMOSD). The aim is to evaluate the safety and efficacy of the treatment with BAFFR CART.

Timeline

Start
2025-12-01
Primary completion
2027-10-01
Completion
2028-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Anti-BAFFR CART Cell therapy — —

Indications