drugset / Trial / NCT06570850
Colistin Monotherapy vs Colsitin-fosfomycine in CRAB Infection
RandomizedParallel-groupOpen-labelTreatment
Summary
The goal of this clinical trial is to evaluate the efficacy of colistin compared with colistin plus fosfomycin against carbapenem-resistant Acinetobacter baumanii infection in Thailand. The main questions it aims to answer the following main questions: 1. Which group has better clinical response at end of treatment 2. Which group has better clinical response at 72 hours and micrological cure at 72 hours and at end of treatment
Timeline
- Start
- 2023-04-01
- Primary completion
- 2025-03
- Completion
- 2025-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Colistimethate | Unknown | 5 mg/kg | Intravenous |
| Comparator | Colistimethate | Unknown | 80 mg | Intravenous |
| Comparator | Fosfomycin | Small molecule | — | Intravenous |