drugset / Trial / NCT06573411

Efficacy and Safety of Finerenone in Patients With Primary Membranous Nephropathy

NCT06573411

Phase 4 Recruiting 116 enrolled First Affiliated Hospital, Sun Yat-Sen University
RandomizedParallel-groupOpen-labelTreatment

Summary

This is a prospective, randomized, multicenter, controlled trial. One hundred sixteen patients with primary membranous nephropathy (PMN) will be randomly divided into the intervention and control groups. The intervention group will be administered maximum tolerable dose of ACEI/ARB and finerenone 20 mg QD. Control patients will be administered maximum tolerable dose of ACEI/ARB. The primary endpoint is the relative change in urinary protein content from baseline to 6 months.

Timeline

Start
2024-09-30
Primary completion
2026-10-30
Completion
2026-10-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Finerenone Small molecule 20 mg