drugset / Trial / NCT06574347

Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC.

NCT06574347

Phase 2 Recruiting 120 enrolled Avistone Biotechnology Co., Ltd.
RandomizedParallel-groupOpen-labelTreatment

Summary

Efficacy and Safety Evaluation of Vebreltinib Plus PLB1004 as the First-line Therapy for Patients With EGFRm+/MET+ Locally Advanced or Metastatic NSCLC.

Timeline

Start
2024-08-07
Primary completion
2026-10-31
Completion
2027-07-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator Osimertinib Small molecule 80 mg Oral
Subject PLB1004 Small molecule 80 mg Oral
Subject Vebreltinib Small molecule 150 mg Oral