drugset / Trial / NCT06576271

A Study of GSK4527363 in Healthy Participants, Systemic Lupus Erythematosus (SLE) Participants, Healthy Chinese, and Japanese Participants and CTD-ILD Participants

NCT06576271

Phase 1 Recruiting 142 enrolled GlaxoSmithKline
RandomizedParallel-groupDouble-blindTreatment

Summary

This study will assess the safety, tolerability, pharmacokinetics, pharmacodynamics and immunogenicity of GSK4527363 in healthy participants (Part A), participants with active SLE (Part B), healthy participants of Chinese and Japanese descent (Part C), and participants with interstitial lung disease associated with connective tissue disease (Part D)

Timeline

Start
2024-09-02
Primary completion
2028-01-11
Completion
2028-01-11

Drugs

EvaluationDrugModalityDoseRoute
Subject Belimumab Monoclonal antibody
Subject GSK4527363 Unknown