drugset / Trial / NCT06589089

Autologous Hematopoietic Stem Cell Boost Study After CAR-T Therapy

NCT06589089

Phase 2 Recruiting 18 enrolled Ruijin Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, single-arm, open study to observe the efficacy and safety of the CART-SCB regimen (Clinical Regimen for the Prospective Study of Autologous Hematopoietic Stem Cell Boost for the Improvement of Bone Marrow Suppression in Patients with High-Risk Immunohematologic Toxicity Lymphoma After Chimeric Antigen Receptor T (CAR-T)-Cell Immunotherapy Therapy) . After the patient has completed CAR-T therapy, if the patient has unrelieved hematologic toxicity, consider infusing a reserve of stem cells; if myelosuppression has not been significantly relieved, stem cell infusion can be performed again.

Timeline

Start
2024-10-15
Primary completion
2025-08
Completion
2025-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Autologous Hematopoietic Stem Cell Cell therapy