drugset / Trial / NCT06593743
The Safety and Dose Response to Single Anal Doses of NRL001
Non-randomizedFactorialOpen-labelBasic science
Summary
Single centre dose-finding and proof-of-concept study in healthy volunteers to assess the effects of single doses of NRL001 on the mean anal resting pressure (MARP). In addition, the pharmacokinetics of NRL001 and subject safety are also examined.
Timeline
- Start
- 2002-12
- Primary completion
- 2004-07
- Completion
- 2013-11-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methoxamine | Unknown | 0.3 % | Other |
| Subject | Methoxamine | Unknown | 1 % | Other |
| Subject | Methoxamine | Unknown | 3 % | Other |
| Subject | Methoxamine | Unknown | 10 mg | Other |
Indications
No indication recorded.