drugset / Trial / NCT06595238

A Study in Participants With Obesity or Overweight With at Least One Weight-related Comorbidity

NCT06595238

Phase 2 Completed 262 enrolled AstraZeneca
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A Phase IIb Randomised, Double-blind, Placebo-controlled Study to Evaluate the Efficacy, Safety and Tolerability of AZD6234 compared with placebo, given once a week as subcutaneous injection for 36 weeks, in male and female participants of at least 18 years of age who are living with obesity (body mass index \[BMI\] ≥ 30 kg/m2), or overweight (BMI ≥ 27 kg/m2) and at least one weight-related comorbidity

Timeline

Start
2024-10-01
Primary completion
2025-12-03
Completion
2025-12-03

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD6234 Small activating RNA (saRNA) Subcutaneous

Indications