drugset / Trial / NCT06598046

A Single-arm, Prospective Phase Ⅱ Clinical Study of Utidelone Combined with Capecitabine in the Treatment of Active Brain Metastasis of TNBC

NCT06598046

Phase 2 Recruiting 48 enrolled Henan Cancer Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study aims to explore the efficacy and safety of the combination therapy of utidelone and capecitabine in the treatment of brain metastases from triple-negative advanced breast cancer, and to search for systemic treatment for brain metastases from triple-negative advanced breast cancer cases.

Timeline

Start
2024-06-19
Primary completion
2026-06-01
Completion
2026-08-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Capecitabine Small molecule 1000 mg/m2 Oral
Subject Epothilone D Small molecule 30 mg/m2 Intravenous

Indications