drugset / Trial / NCT06601517

A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects.

NCT06601517

Phase 1 Not yet recruiting 30 enrolled Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to characterize the effect of HDM1002 on the PK of single dose of repaglinide, atorvastatin, digoxin and rosuvastatin in healthy adult subjects. The safety and tolerability of HDM1002 with repaglinide, atorvastatin, digoxin and rosuvastatin when given separately or together will also be evaluated.

Timeline

Start
2024-10
Primary completion
2025-02
Completion
2025-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Atorvastatin Small molecule Oral
Subject Digoxin Other / unclassified Oral
Subject HDM1002 Unknown Oral
Subject Repaglinide Small molecule Oral
Subject Rosuvastatin Small molecule Oral

Indications

No indication recorded.