drugset / Trial / NCT06606327
Diazoxide Suppression Test P&F Study
Phase 1
Recruiting
10 enrolled
Columbia University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collabUniversity of Pisa · collab
NaSingle-groupOpen-labelBasic science
Summary
The goal of this study is to learn about how the hormone insulin controls blood sugar. The main question it aims to answer is about how much insulin the body actually needs to maintain a normal blood sugar level. People with obesity and high insulin levels will receive eight doses of diazoxide, a drug that suppresses the pancreas's production of insulin, and will have their fasting blood sugar and insulin levels checked daily while taking the drug.
Timeline
- Start
- 2024-10-23
- Primary completion
- 2027-11
- Completion
- 2028-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Diazoxide | Unknown | 3 mg/kg | Oral |