Effect of Cannabis on Cigarette Use Behavior

Phase 1 Recruiting 100 enrolled Johns Hopkins University National Institute on Drug Abuse (NIDA) · collab

RandomizedFactorialQuadruple-blindBasic science

Summary

The purpose of this study is to determine the impact of tetrahydrocannabinol (THC) administration on motivational, subjective, and physiological effects of cigarettes. The study's goals are to test demand for cigarettes, tobacco craving, affect, heart rate, blood pressure, expired breath carbon monoxide, and cognitive performance. Researchers will compare multiple doses of THC and a placebo in participants who smoke cigarettes and either smoke or vape THC in the laboratory.

Timeline

Start: 2025-01-22
Primary completion: 2029-04-01
Completion: 2029-10-01

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Dronabinol	Other / unclassified	5 mg	Other
Subject	Dronabinol	Other / unclassified	30 mg	Other

Indications

No indication recorded.