drugset / Trial / NCT06617026

Short-Term Outcome of Medical Vs. Surgical Management Of Chronic Anal Fissure

NCT06617026

Phase 1/2 Completed 99 enrolled Suez Canal University
RandomizedParallel-groupOpen-labelTreatment

Summary

Several topical agents have been proposed for Chronic anal fissure (CAF) treatment with the common goal of increasing anodermal blood flow to promote healing but approaching the use of medical treatment in CAFs is not standardized yet. Thus, the present study aimed to compare the efficacy and safety of Sucralfate (Emoflon®), the combination of azadirachtin and hyperforin (HyperOil®) and the traditional surgical treatment (lateral sphincterotomy) in patients with CAFs.

Timeline

Start
2024-08-30
Primary completion
2024-10-01
Completion
2024-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Azadirachtin Unknown Topical
Subject Hyperforin Unknown Topical
Subject Sucralfate Unknown Topical