drugset / Trial / NCT06617026
Short-Term Outcome of Medical Vs. Surgical Management Of Chronic Anal Fissure
RandomizedParallel-groupOpen-labelTreatment
Summary
Several topical agents have been proposed for Chronic anal fissure (CAF) treatment with the common goal of increasing anodermal blood flow to promote healing but approaching the use of medical treatment in CAFs is not standardized yet. Thus, the present study aimed to compare the efficacy and safety of Sucralfate (Emoflon®), the combination of azadirachtin and hyperforin (HyperOil®) and the traditional surgical treatment (lateral sphincterotomy) in patients with CAFs.
Timeline
- Start
- 2024-08-30
- Primary completion
- 2024-10-01
- Completion
- 2024-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Azadirachtin | Unknown | — | Topical |
| Subject | Hyperforin | Unknown | — | Topical |
| Subject | Sucralfate | Unknown | — | Topical |