drugset / Trial / NCT06621173

A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients

NCT06621173 ↗

Phase 0 Recruiting 9 enrolled Shanghai Changzheng Hospital
NaSingle-groupOpen-labelTreatment

Summary

This trial is a single-arm, open-label, exploratory first-in-human clinical study designed to evaluate the safety and tolerability of HNF4α srRNA injection in patients with locally unresectable or metastatic colorectal cancer, and to preliminarily explore its effectiveness in treating metastatic colorectal cancer.

Timeline

Start
2024-11-12
Primary completion
2026-07
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject HNF4α srRNA Unknown 25 ug Intravenous
Subject HNF4α srRNA Unknown 50 ug Intravenous
Subject HNF4α srRNA Unknown 100 ug Intravenous

Indications