drugset / Trial / NCT06621173
A Clinical Trial Evaluating the Safety and Efficacy of Intravenous HNF4α SrRNA in Treating Metastatic CRC Patients
NaSingle-groupOpen-labelTreatment
Summary
This trial is a single-arm, open-label, exploratory first-in-human clinical study designed to evaluate the safety and tolerability of HNF4α srRNA injection in patients with locally unresectable or metastatic colorectal cancer, and to preliminarily explore its effectiveness in treating metastatic colorectal cancer.
Timeline
- Start
- 2024-11-12
- Primary completion
- 2026-07
- Completion
- 2026-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | HNF4α srRNA | Unknown | 25 ug | Intravenous |
| Subject | HNF4α srRNA | Unknown | 50 ug | Intravenous |
| Subject | HNF4α srRNA | Unknown | 100 ug | Intravenous |