drugset / Trial / NCT06627270

Antibiotic Treatment Effects on Intratumoral Bacteria Modulation in Surgical Patients With Oral Cancer

NCT06627270

Phase 2 Recruiting 30 enrolled Case Comprehensive Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The goal of this phase II single arm clinical study is to evaluate the effect of antibiotics (metronidazole) and oral chlorhexidine (CHX) in reducing the bacteria load within tumors of patients undergoing surgery for oral cancer.

Timeline

Start
2025-03-11
Primary completion
2026-10-01
Completion
2027-10-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Metronidazole Small molecule 500 mg Oral