drugset / Trial / NCT06628947

A Phase II Study of Intravitreal KIO-301 in Patients With Late-stage Retinitis Pigmentosa

NCT06628947 ↗

Phase 2 Recruiting 36 enrolled Kiora Pharmaceuticals, Inc.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The goal of the study is to investigate the safety, tolerability and efficacy of up to 3 doses of KIO-301 administered by intravitreal (IVT) injection bilaterally every 6 weeks in patients with late-stage retinitis pigmentosa (RP). Late-stage RP patients will include those patients with No Light Perception (NLP), or Low Vision (LV).

Timeline

Start
2025-08-29
Primary completion
2027-08
Completion
2027-08

Drugs

EvaluationDrugModalityDoseRoute
Subject KIO-300 Unknown 25 ug Intravitreal
Subject KIO-300 Unknown 50 ug Intravitreal
Subject KIO-300 Unknown 100 ug Intravitreal

Indications