drugset / Trial / NCT06646198

TIPS Plus Half-dose Donafenib in AHCC with PVTT-associated Portal Hypertension

NCT06646198

Phase 2 Recruiting 40 enrolled Fei Gao
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) plus half-dose donafenib (a kind of anti-angiogenesis agents) in advanced hepatocellular carcinoma (BCLC-C Stage) accompanied by tumor thrombosis-associated portal hypertension.

Timeline

Start
2024-10-08
Primary completion
2026-05-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Donafenib Small molecule 100 mg Oral