drugset / Trial / NCT06649851
G-CSF After Chemo-radiation in Patients With Glioblastoma
RandomizedParallel-groupOpen-labelTreatment
Summary
This research study involves the study of granulocyte colony stimulating factor (G-CSF) in patients with MGMT-methylated glioblastoma multiforme (GBM) that are undergoing standard chemoradiation. The study aims to evaluate G-CSF's effects on brain health and cognitive function. The name of the study drugs involved in this study are: * G-CSF (also called Filgrastim) * Temozolomide (TMZ), a standard of care chemotherapy drug
Timeline
- Start
- 2025-04-02
- Primary completion
- 2027-01-31
- Completion
- 2030-01-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | filgrastim | Protein / enzyme biologic | 5 ug/kg | Subcutaneous |
| Subject | filgrastim | Protein / enzyme biologic | 7 ug/kg | Subcutaneous |