drugset / Trial / NCT06653153

A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)

NCT06653153 ↗

Phase 3 Active not recruiting 1400 enrolled Eli Lilly and Company
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to measure the difference in time to developing or worsening memory, thinking, or functional problems due to Alzheimer's disease occurring in participants receiving study drug compared to placebo. Participation could last up to 255 weeks including screening, a double-blind treatment period, and a double-blind observation period. In addition, eligible participants who receive placebo during the double-blind treatment period may choose to extend their study participation to receive open-label remternetug in an extension period.

Timeline

Start
2024-10-24
Primary completion
2029-04
Completion
2030-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Remternetug Monoclonal antibody — Subcutaneous

Indications