drugset / Trial / NCT06660563

A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)

NCT06660563

Phase 1 Active not recruiting 19 enrolled Janssen Research & Development, LLC
NaSequentialOpen-labelTreatment

Summary

The purpose of this study is to determine the recommended phase 2 regimen (RP2R) for JNJ-80948543 in combination with JNJ-75348780 (Part 1: Dose Escalation) and to further assess the safety of JNJ-80948543 at the RP2R in combination with JNJ-75348780 (Part 2: Dose Expansion).

Timeline

Start
2024-10-22
Primary completion
2026-01-19
Completion
2027-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject JNJ-80948543 Unknown Subcutaneous
Background REZETAMIG Monoclonal antibody Subcutaneous

Indications