drugset / Trial / NCT06660563
A Study of JNJ-80948543 in Combination With Other CD3 T-Cell Engagers in Participants With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (R/R B-Cell NHL)
NaSequentialOpen-labelTreatment
Summary
The purpose of this study is to determine the recommended phase 2 regimen (RP2R) for JNJ-80948543 in combination with JNJ-75348780 (Part 1: Dose Escalation) and to further assess the safety of JNJ-80948543 at the RP2R in combination with JNJ-75348780 (Part 2: Dose Expansion).
Timeline
- Start
- 2024-10-22
- Primary completion
- 2026-01-19
- Completion
- 2027-03-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | JNJ-80948543 | Unknown | — | Subcutaneous |
| Background | REZETAMIG | Monoclonal antibody | — | Subcutaneous |