drugset / Trial / NCT06663319

A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers

NCT06663319 ↗

Phase 1 Recruiting 260 enrolled Janssen Research & Development, LLC
Non-randomizedSequentialOpen-labelTreatment

Summary

The purpose of this study is to determine the putative recommended phase 2 dose(s) (RP2Ds) and best way to take (optimal route of administration) JNJ-89402638 and to determine the safety of JNJ-89402638 at the RP2D(s) in participants with metastatic colorectal cancer (mCRC) and metastatic gastric cancer (mGAC) and to determine the safety and tolerability of JNJ-89402638 in combination with bevacizumab or biosimilar with or without chemotherapy in participants with mCRC.

Timeline

Start
2024-10-15
Primary completion
2028-02-25
Completion
2028-07-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody — —
Subject JNJ-89402638 Unknown — —

Indications