drugset / Trial / NCT06663319
A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers
Non-randomizedSequentialOpen-labelTreatment
Summary
The purpose of this study is to determine the putative recommended phase 2 dose(s) (RP2Ds) and best way to take (optimal route of administration) JNJ-89402638 and to determine the safety of JNJ-89402638 at the RP2D(s) in participants with metastatic colorectal cancer (mCRC) and metastatic gastric cancer (mGAC) and to determine the safety and tolerability of JNJ-89402638 in combination with bevacizumab or biosimilar with or without chemotherapy in participants with mCRC.
Timeline
- Start
- 2024-10-15
- Primary completion
- 2028-02-25
- Completion
- 2028-07-19
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bevacizumab | Monoclonal antibody | — | — |
| Subject | JNJ-89402638 | Unknown | — | — |