drugset / Trial / NCT06665100

PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)

NCT06665100

RandomizedParallel-groupQuadruple-blindPrevention

Summary

The purpose of this research study is to try to see whether an experimental drug, PUL 042 Inhalation Solution (PUL 042), is effective in reducing the severity of lung infections in patients with hematologic malignancies and recipients of hematopoietic stem cell transplantation with documented viral infections due to PIV, hMPV, or RSV. PUL-042 or a placebo will be administered 3 times over a 6-day period. The total duration of the study will be approximately 30 days.

Timeline

Start
2025-06-27
Primary completion
2027-04
Completion
2027-05

Drugs

EvaluationDrugModalityDoseRoute
Subject PUL-042 Oligonucleotide (other) Inhaled