drugset / Trial / NCT06665217

G-Pola-ZLP in Diffuse Large B-Cell Lymphoma

NCT06665217

Phase 2 Not yet recruiting 80 enrolled Navy General Hospital, Beijing
NaSingle-groupOpen-labelTreatment

Summary

The goal of this phase 2 trial is to test the safety and efficacy of G-Pola-ZLP as induction therapy in patients with DLBCL.

Timeline

Start
2025-09-24
Primary completion
2029-01
Completion
2030-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Glofitamab Monoclonal antibody 30 mg
Subject Lenalidomide Other / unclassified 25 mg Oral
Subject Polatuzumab Vedotin Other / unclassified 1.8 mg/kg Intravenous
Subject Prednisone Other / unclassified 60 mg/m2 Oral
Subject Zanubrutinib Small molecule 160 mg Oral