drugset / Trial / NCT06671340
Chronic Dorzagliatin on Insulin and Incretin Function in Intermediate Hyperglycemia and Type 2 Diabetes
NaSingle-groupOpen-labelTreatment
Summary
A total of 30 subjects will be recruited 15 with intermediate hyperglycemia and 15 in the tyep 2 diabetes group respectively. Eligible participants will undergo hyperglycemic-clamp/oral glucose tolerance at baseline and after 4 weeks of dorzagliatin treatment.
Timeline
- Start
- 2025-04-02
- Primary completion
- 2025-12-30
- Completion
- 2026-01-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dorzagliatin | Small molecule | 50 mg | Oral |
| Subject | Dorzagliatin | Small molecule | 75 mg | Oral |