drugset / Trial / NCT06684184

Blinatumomab in Refractory Myasthenia Gravis (BLINA-MG)

NCT06684184

Phase 2/3 Not yet recruiting 10 enrolled Zhongming Qiu
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to evaluating the efficacy and safety of Blinatumomab in the treatment of refractory myasthenia gravis and exploring the immunological mechanisms of Blinatumomab therapy in refractory myasthenia gravis. The main questions it aims to answer are: Will Blinatumomab improve the symptoms of participants? What medical problems do participants have when using Blinatumomab? Participants will: Continuous intravenous infusion of Blinatumomab for 5 days, pause for one week, and continue continuous intravenous infusion for 5 days Visit the clinic once every 1 month for checkups and tests Keep a diary of their symptoms

Timeline

Start
2024-11-30
Primary completion
2025-12-31
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Blinatumomab Monoclonal antibody 38.5 ug Intravenous

Indications