Non-Steroidal Anti-Inflammatory Drugs in Acute Myocarditis

Summary

Prospective, randomized, multicenter, open-label clinical trial to evaluate the safety and efficacy of a 3-week ibuprofen tapering regimen compared to conventional analgesic treatment (acetaminophen) in patients with acute myocarditis and left ventricular ejection fraction ≥50%. The objective is to assess the reduction in late gadolinium enhancement on cardiac magnetic resonance imaging at 6-month follow-up.

Timeline

Start

2025-04-28

Primary completion

2027-04

Completion

2027-10

Drugs

Indications