drugset / Trial / NCT06693505

The Effect of Caffeinated Chewing Gum on Cognitive Performance in Night-shift Emergency Physicians

NCT06693505

Completed 14 enrolled China Medical University Hospital
RandomizedCrossoverQuadruple-blindHealth-services research

Summary

This study aimed to examine the impact of caffeinated chewing gum on the cognitive performance of night-shift emergency physicians in a partially sleep-deprived state. A randomized, double-blind crossover controlled experimental design was employed in which fourteen (Age: 29.9 ± 1.44; height: 176.5±5.3; weight: 78.1±13.4) emergency physicians consumed either caffeinated chewing gum (CAF) containing 200 mg caffeine or a caffeine-free placebo gum (PLA) for 10 minutes at 03:30 am during their first 8-hour night shift after at least one day off, and completed cognitive performance tests before shift, mid-shift (10 minutes after gum chewing), and after shift, including included Corsi block test, Task-switching paradigm, Stroop Test, Visual search, and Wisconsin Card Sorting Task. Sleep quality was assessed subjectively by a single question score, and objectively by ActiGraph for one night on the off day and the last sleep before the first night shift, to evaluate the effect of sleep quality on cognitive performance.

Timeline

Start
2022-10-01
Primary completion
2024-08-25
Completion
2024-08-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Caffeine Small molecule 200 mg

Indications