drugset / Trial / NCT06693674

Effect of Sacubitril-Valsartan on Cardiac Structure and Function

NCT06693674

RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to compare changes in cardiac structure and function, biomarkers, and patient reported outcomes between adults with congenital heart disease (ACHD) randomized to angiotensin receptor-neprilysin inhibitor (ARNI) therapy vs placebo.

Timeline

Start
2025-02-03
Primary completion
2026-12
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject LCZ696 Unknown 24 mg Oral
Subject LCZ696 Unknown 49 mg Oral
Subject LCZ696 Unknown 97 mg Oral