drugset / Trial / NCT06695013

Immunobridging/Maintenance Therapy Versus Non-bridging Therapy in CAR-T Therapy for Low-risk R/R B-NHL

NCT06695013

Phase 2 Recruiting 144 enrolled Ruijin Hospital
RandomizedParallel-groupOpen-labelTreatment

Summary

This study aims to explore whether adding immunotherapy bridging treatment for low-risk refractory/relapsed B-NHL can demonstrate better outcomes, in order to find the most effective treatment plan for low-risk patients.

Timeline

Start
2024-11-20
Primary completion
2026-11-20
Completion
2027-03-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Zanubrutinib Small molecule 160 mg Oral
Background Tislelizumab Monoclonal antibody 200 mg Intravenous