13-cis Retinoic Acid (Isotretinoin) and Sperm Production

Summary

This study aims to evaluate the effectiveness of weekly administration of isotretinoin (40 mg) in increasing sperm production in men with oligozoospermia, a condition characterized by a low sperm count. Participants will be randomized into two groups: one receiving isotretinoin and the other a placebo. The primary outcome will be the change in sperm production over 20 weeks of treatment.

Timeline

Start

2025-03-01

Primary completion

2027-12-01

Completion

2027-12-01

Drugs

Indications