drugset / Trial / NCT06699602

A Study of Cemiplimab and Fianlimab in People With Clear Cell Renal Cell Carcinoma

NCT06699602

Phase 2 Recruiting 10 enrolled Memorial Sloan Kettering Cancer Center
NaSingle-groupOpen-labelTreatment

Summary

The researchers are doing this study to find out whether it is practical (feasible) to give cemiplimab and fianlimab before a nephrectomy and whether it causes any delays with surgery in people with kidney cancer. The researchers will also look at whether cemiplimab and fianlimab given before a nephrectomy is a safe and effective treatment approach and if there is a change in the size of the tumor following immunotherapy prior to planned surgery.

Timeline

Start
2025-02-11
Primary completion
2028-02
Completion
2028-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cemiplimab Monoclonal antibody Intravenous
Subject Fianlimab Monoclonal antibody Intravenous

Indications