drugset / Trial / NCT06700655

A Clinical Study on Co-transplantation of Autologous Limbal Stem Cells and Corneal Stromal Stem Cells to Repair Corneal Injury

NCT06700655 ↗

Phase 1/2 Not yet recruiting 60 enrolled Zhongshan Ophthalmic Center, Sun Yat-sen University
RandomizedParallel-groupSingle-blindTreatment

Summary

This study aims to: 1) verify the feasibility of treating limbal stem cell deficiency (LSCD) caused by chemical injury with autologous limbal stem cell transplantation combined with corneal stromal stem cell transplantation; 2) evaluate the corneal healing patterns following autologous stem cell transplantation; and 3) establish a clinical intervention protocol based on autologous corneal stem cell transplantation. Sixty cases of single-eye LSCD were included.

Timeline

Start
2024-12-01
Primary completion
2028-12-01
Completion
2029-03-01

Drugs

EvaluationDrugModalityDoseRoute
Subject corneal limbal stem cells Cell therapy — —
Subject corneal stromal stem cells Cell therapy — —