drugset / Trial / NCT06705101
Gabapentin and Pressor Response to Intubation
RandomizedParallel-groupSingle-blindPrevention
Summary
This study evaluates the effectiveness of oral gabapentin in reducing the pressor response (increased MAP, HR, and BP) during laryngoscopic intubation. It is a prospective, double-blind randomized controlled trial involving 144 patients undergoing elective surgery. Gabapentin 300 mg or placebo will be administered preoperatively, with hemodynamic parameters monitored before and after intubation. The study aims to determine if gabapentin attenuates the sympathetic stress response compared to placebo.
Timeline
- Start
- 2024-12-15
- Primary completion
- 2025-06-15
- Completion
- 2025-07-16
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gabapentin | Small molecule | 300 mg | Oral |
Indications
No indication recorded.