drugset
drugset / Trial / NCT06707194

Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis

NCT06707194 ↗

Phase 4 Recruiting 340 enrolled Nanfang Hospital, Southern Medical University
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of the study is to verify the clinical feasibility of Benzathine penicillin (BPG) /Etanercept (ETN) combination regimen in patients with spondyloarthritis (SpA) and at the same time compare Benzathine penicillin /Etanercept combination regimen and Etanercept maintenance therapy in reducing disease activity, improving patients' clinical symptoms and body function scores, enhancing quality of life, improving imaging performance and safety.

Timeline

Start
2025-06-14
Primary completion
2027-03-01
Completion
2027-07-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Benzathine Penicillin Small molecule 1.2e+06 iu Intramuscular
Background Etanercept Protein / enzyme biologic 25 mg Subcutaneous

Indications

ankylosing spondylitis