drugset / Trial / NCT06719557

A Study of the Effect of Itraconazole and Phenytoin on Calderasib (MK-1084) in Healthy Adults (MK-1084-008)

NCT06719557

Phase 1 Completed 28 enrolled Merck Sharp & Dohme LLC
Non-randomizedParallel-groupOpen-labelBasic science

Summary

The goal of this study is to learn what happens to calderasib in a healthy person's body over time, called a pharmacokinetic (PK) study. Researchers want to compare the amount of calderasib when it is taken as a single dose; with multiple doses of itraconazole, or with multiple doses of phenytoin.

Timeline

Start
2024-05-20
Primary completion
2024-07-30
Completion
2024-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Calderasib Unknown Oral
Subject Itraconazole Small molecule Oral
Subject Phenytoin Unknown Oral

Indications

No indication recorded.