drugset / Trial / NCT06722911

Study of Adjuvant Nimotuzumab Combined with Nab-paclitaxel+ Gemcitabine in EGFR-positive Pancreatic Cancer

NCT06722911

Phase 2 Recruiting 57 enrolled Zhejiang Provincial People's Hospital
NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, single-arm trial. The main purpose of the study is to evaluate the efficacy and safety of Nimotuzumab combined with nab-paclitaxel+ gemcitabine (AG regimen) for postoperative adjuvant treatment of pancreatic cancer with EGFR-positive.

Timeline

Start
2024-11-15
Primary completion
2028-09-30
Completion
2028-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Nimotuzumab Monoclonal antibody 400 mg
Subject Nimotuzumab Monoclonal antibody 600 mg
Subject Paclitaxel Small molecule 125 mg/m2 Intravenous

Indications