A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study Evaluating the Efficacy and Safety of SHR-1918 in Patients With Homozygous Familial Hypercholesterolemia

Summary

This is a multicenter, randomized, double-blind, placebo-controlled phase III clinical study to assess the reduction of low-density lipoprotein cholesterol (LDL-C) by SHR-1918 in patients with homozygous familial hypercholesterolemia (HoFH).

Timeline

Start

2025-02-13

Primary completion

2025-08-25

Completion

2025-11-18

Outcome

Met primary endpoint

release “研究结果显示，第12周时，相比安慰剂，芮弗西拜单抗组低密度脂蛋白胆固醇（LDL-C）的降幅达64.2%” hengrui.com ↗

Drugs

Indications